10 Best enzymes of 2025

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Best Choice

1

Physician's CHOICE
Physician's CHOICE Advanced Gut Health Bundle: 60 Billion Probiotics 30ct + Digestive Enzymes 60ct for Digestive, Gut, and Immune Health Supports Occasional Constipation, Diarrhea, Gas, and Bloating
Main highlights

Gut Health and Comfort
Combines 60 billion CFU probiotics and digestive enzymes for optimal gut health and comfort.

Ideal for Digestive Issues
Perfect for supporting digestion, reducing bloating, gas, and indigestion.

Customer Favorite: Digestive Relief
Praised for its effectiveness in relieving digestive discomfort and promoting regularity.
Key specs
- Form:Bundle
- Use:Gut health, nutrient absorption
- Target Symptoms:Digestive discomfort, bloating
- Packaging:Comprehensive gut health solution
- Active Ingredient:Probiotics, Digestive Enzymes
9.9

Exceptional

Our Rating
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Value for Money

2

Pure Encapsulations
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules
Main highlights

Enhanced Nutrient Absorption
Contains vegetarian enzymes to improve nutrient bioavailability and digestion.

Ideal for Digestive Support
Perfect for breaking down proteins, dairy, fiber, and sugars.

Highly Praised for Bloating Relief
Customers frequently commend its effectiveness in reducing bloating.
Key specs
- Usage:Supports digestion
- Form:Capsule
- Enzyme Blend:Vegetarian enzyme blend
- Origin:N/A
- Dietary Restrictions:Free from common allergens
9.7

Exceptional

Our Rating

8.9
Flavor

8.4
worth the money
3

NOW Foods
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

49% Off
Main highlights

Supports Healthy Digestion
NOW Super Enzymes blend aids digestion with bromelain, ox bile, pancreatin, and papain.

Ideal for Post-Surgery Recovery
Beneficial for individuals post-gallbladder surgery or with digestive issues.

Highly Praised for Digestive Relief
Customers appreciate its ability to alleviate bloating and discomfort.
Key specs
- Usage:Supports healthy digestion
- Form:Capsule
- Enzyme Blend:Bromelain, ox bile, pancreatin, papain
- Origin:USA
- Dietary Restrictions:Soy Free, Gluten Free
9.5

Excellent

Our Rating

9.7
quality of ingredients

9.5
simple to consume

9.3
worth the money
4

Physician's CHOICE
Physician's CHOICE Digestive Enzymes - Multi Enzymes, Organic Prebiotics & Probiotics for Digestive Health & Gut Health - Meal Time Discomfort Relief & Bloating - Dual Action Approach - 60 CT

15% Off
Main highlights

Comprehensive Digestive Support
Features 16 enzymes, probiotics, and prebiotics for optimal digestion.

Ideal for Meal Time Relief
Perfect for those experiencing bloating or digestive distress post-meals.

Highly Praised for Gut Health
Customers love its effectiveness in supporting gut and digestive health.
Key specs
- Usage:Aid digestion
- Form:Capsules
- Enzyme Blend:16 beneficial enzymes
- Origin:USA
- Dietary Restrictions:N/A
9.4

Excellent

Our Rating
5

Source Naturals
Source Naturals Essential Enzymes 500mg Bio-Aligned Multiple Supplement Herbal Defense for Digestion, Gas & Constipation Relief - Strong Immune System Support* - 120 Capsules

30% Off
Main highlights

Comprehensive Digestive Support
Transforms food into essential nutrients with multiple enzymes for proteins, fats, and carbohydrates.

Versatile Use Cases
Ideal for individuals with digestive issues like bloating or nutrient absorption challenges.

Customer Praised Efficiency
Highly effective in reducing bloating and improving digestion, as noted by users.
9.3

Excellent

Our Rating

9.9
quality of ingredients

9.9
Flavor

9.7
simple to consume
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6

Zenwise Health

Zenwise Health Digestive Enzymes and Bromelain for Gut Health - Probiotic Multi Enzymes with Prebiotics and Probiotics for Women and Men for Digestive Health and Bloating Relief for Digestion - 45 CT

13% Off
9.2

Excellent

Our Rating
7

Garden of Life
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

24% Off
Main highlights

Organic Digestive Support
Formulated with 29 organic fruits, vegetables, and 13 enzymes.

Ideal for Digestive Relief
Perfect for those seeking improved digestion and nutrient absorption.

Praised Tropical Flavor
Customers love the refreshing tropical fruit taste.
9.1

Excellent

Our Rating

9.5
simple to consume

9.5
Absorbency

9.1
Flavor
8

Double Wood Supplements
Digestive Enzymes - 800mg Blend of All 10 Most Essential Digestive and Pancreatic Enzymes (Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase) by Double Wood
Main highlights

Comprehensive Enzyme Blend
Contains all 10 essential digestive enzymes for complete digestive support.

Ideal for Digestive Health
Perfect for individuals needing support for protein, fat, and carb breakdown.

Praised for Gut Health
Customers love its impact on improving gut health and digestion.
Key specs
- Usage:Digestive aid
- Form:Capsule
- Enzyme Blend:Amylase, Lipase, Bromelain
- Origin:USA
- Dietary Restrictions:Non-GMO, Gluten Free
9.0

Excellent

Our Rating

9.9
worth the money

9.9
simple to consume

9.9
quality of ingredients
9

NOW Foods
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain, Super Enzymes, 90 Tablets

44% Off
Main highlights

Key Features
Enhances digestion by breaking down fats, carbs, & protein, ensuring optimal nutrient absorption. Easy-to-swallow, made in the USA by a family-owned company since 1968.

Ideal Use Cases
Perfect for individuals seeking to improve digestive health, especially after meals rich in fats, carbohydrates, and proteins to optimize nutrient intake.

Customer Praise
Most reviews highlight its effectiveness in easing digestive discomfort and promoting better overall digestive health, with noticeable results.
Key specs
- Usage:Optimizes Nutrient Availability
- Form:Tablet
- Enzyme Blend:Fats, Carbs & Protein
- Origin:USA
- Dietary Restrictions:N/A
8.9

Very Good

Our Rating

8.0
simple to consume

8.0
Comfort

8.0
worth the money
10

BIOptimizers
BiOptimizers MassZymes - Complete Digestive Enzymes Supplement for Gut Health - Bloating Relief for Men and Women - Lipase Amylase Bromelain Digestive Enzymes (120 Capsules)

13% Off
Main highlights

Key Features
Enhances digestion, boosts energy, and improves mental clarity with proteolytic enzymes and AstraZyme. Vegan-friendly with no fillers or artificial ingredients.

Ideal Use Cases
Great for those experiencing digestive issues, athletes seeking faster recovery, and individuals wanting increased energy and mental focus.

Customer Praise
Most reviews highlight significant improvements in digestive health, reduced bloating, and increased energy as the top benefits.
Key specs
- Usage:Digestive enzyme supplement
- Form:Capsule
- Enzyme Blend:MassZymes 3.0 with AstraZyme
- Origin:Plant-based
- Dietary Restrictions:Vegan, dairy-free, soy-free
8.8

Very Good

Our Rating

9.7
simple to consume

8.0
Flavor

8.0
Absorbency

10 Best enzymes of 2025

1

Physician's CHOICE Advanced Gut Health Bundle: 60 Billion Probiotics 30ct + Digestive Enzymes 60ct for Digestive, Gut, and Immune Health Supports Occasional Constipation, Diarrhea, Gas, and Bloating

How do we rank?

How do we rank?

Analyzing top stores

2

Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

8.9

8.4

3

NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

9.7

9.5

9.3

4

Physician's CHOICE Digestive Enzymes - Multi Enzymes, Organic Prebiotics & Probiotics for Digestive Health & Gut Health - Meal Time Discomfort Relief & Bloating - Dual Action Approach - 60 CT

5

Source Naturals Essential Enzymes 500mg Bio-Aligned Multiple Supplement Herbal Defense for Digestion, Gas & Constipation Relief - Strong Immune System Support* - 120 Capsules

9.9

9.9

9.7

6

Zenwise Health Digestive Enzymes and Bromelain for Gut Health - Probiotic Multi Enzymes with Prebiotics and Probiotics for Women and Men for Digestive Health and Bloating Relief for Digestion - 45 CT

7

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

9.5

9.5

9.1

8

Digestive Enzymes - 800mg Blend of All 10 Most Essential Digestive and Pancreatic Enzymes (Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase) by Double Wood

9.9

9.9

9.9

9

NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain, Super Enzymes, 90 Tablets

8.0

8.0

8.0

10

BiOptimizers MassZymes - Complete Digestive Enzymes Supplement for Gut Health - Bloating Relief for Men and Women - Lipase Amylase Bromelain Digestive Enzymes (120 Capsules)

9.7

8.0

8.0

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